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產(chǎn)品規(guī)格
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BN40715R-100ul
100ul
￥2360.00
交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB
BN40715R-200ul
200ul
￥3490.00
交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB
產(chǎn)品描述
| 英文名稱 | KGF |
| 中文名稱 | 纖維母細胞生長因子7抗體 |
| 別 名 | FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7;HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding growth factor 7. |
| 研究領域 | 腫瘤 免疫學 信號轉(zhuǎn)導 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應用 | WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KGF:32-110/194 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Subunit: Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Epithelial cell. Similarity: Belongs to the heparin-binding growth factors family. SWISS: P21781 Gene ID: 2252 Database links: Entrez Gene: 2252 Human Entrez Gene: 14178 Mouse Omim: 148180 Human SwissProt: P21781 Human SwissProt: P36363 Mouse Unigene: 567268 Human Unigene: 330557 Mouse Unigene: 98842 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. KGF/FGF7 (Fibroblast growth factor 7) 又稱：HBGF-7 纖維母細胞生長因子7，是FGF家族的主要成員之一。 FGF家族參與細胞生長、組織修復、胚胎生長發(fā)育、組織器官的形成、腫瘤的生長和侵潤等諸多生理病理功能。 成纖維細胞生長因子7的促增生作用主要來源于角化上皮細胞而不是間質(zhì)細胞和內(nèi)皮細胞，因此人們又稱之為：角化上皮細胞生長因子（KGF）。 |
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